Hi, I'm Lorna and I don't use a mouse. I have had RSI issues since a bad workstation setup at work in 2006. I've tried a number of extra hardware modifications but what works best for me is to use the keyboard and only the keyboard, so I'm in a good position and never reaching for anything else (except my coffee cup!). I rather unwisely took a job which required me to use either a mac or Windows (I've been a linux user until now and also had the ability to choose my tools carefully) so here is my cheatsheet of the apps, tricks and keyboard shortcuts I'm using, mostly for my own reference. Since keyboard-only use is also great for productivity, you may also find some of these ideas useful, in which case at least something good has come of this :)
There's more detail on a few of these apps but here is a quick overview of the tools I've installed and found helpful
| Tool | Link | Comments | 
|---|---|---|
| vim | ||
| chrome + vimium | ||
| shortcat | ||
| alfred | ||
| hyperswitch | ||
| spectacle | ||
| iterm2 | ||
Cmd + , (comma) to access preferences for the current app
Cmd + F2 focuses the top menu bar (you can turn off the machine from here)
Cmd + F3 focuses the dock
related: you probably want to turn off Ctrl + F1 which enables and disables the above!  Look in the keyboard settings.
Lock the screen: Ctrl + Shift + eject/power or say "lock" to Alfred.
These are a pain to set up but I love them because it means I'm looking at fewer apps on one screen and it's easier to jump to the one I want without a lot of Cmd + tab to switch between applications.  To configure:
- 
Go to "Mission Control" using
Ctrl + up - 
Hover your mouse at the top of the screen (yes, I do have a mouse, I just had to go and find it out of a cupboard) and it will unfold to show a bar where you can add as many spaces as you like. Check the options in "System Preferences" -> "Mission Control" to decide whether you want this per screen or not. Mine are not, the space spans both monitors.
 
You can move between spaces with Ctrl + left/right or there are keyboard shortcuts to enable via the keyboard settings area which enable going to a specific space by number Ctrl + 1 etc.  This probably is more useful if you don't allow the mac to re-order your spaces as it pleases (this is a setting, I like mine to stay where I put them but YMMV).
Switching windows within an app Cmd + backtick.
In iterm2, also press Cmd + Alt + [number] where the number is displayed in the window bar.  For switching between tabs, you can use Cmd + number - this also works in Chrome.  For other apps try Cmd + Shift + ] or [.
Alt + space to run any program.  Alfred can do a hundred more things than this, well worth more research!
Shortcat might be the killer app for me on OS X. It can "see" and make "clickable" more or less any control in an application, including the content. To use:
- 
Type
Cmd + Shift + space - 
If the thing you want is labelled in words, start typing the words or the first letter of each word. If not, type a dot/period, which will show everything.
 - 
If the thing you want is now highlighted in blue rather than yellow, press enter.
 - 
If not, hold
Ctrland start typing the label. When the highlight is on the thing you want, press enter. 
Note that you will need to allow Shortcat some accessibility permissions to run. The installation process will prompt you or you can find it in "System Settings" -> "Privacy" -> "Accessibility"