from pycoin.tx.tx_utils import create_signed_tx
from pycoin.services.blockcypher import BlockcypherProvider

# inspect your spendables
spendables = [x.as_text() for x in BlockcypherProvider().spendables_for_address(address=FROM_ADDRESS)]

# sign TX
signed_tx = create_signed_tx(
    spendables=spendables,
    payables=[TO_ADDRESS],
    wifs=[WIF],
    fee=FEE_IN_SATOSHIS,
)

# inspect signed TX and then use a pushtx service to broadcast
signed_tx.as_hex()