(C-x means ctrl+x, M-x means alt+x)
The default prefix is C-b. If you (or your muscle memory) prefer C-a, you need to add this to ~/.tmux.conf:
git clone [email protected]:YOUR-USERNAME/YOUR-FORKED-REPO.git
cd into/cloned/fork-repo
git remote add upstream git://github.com/ORIGINAL-DEV-USERNAME/REPO-YOU-FORKED-FROM.git
git fetch upstream